stopping arimidex after 5 years

Barbara, according to my radiologist when we talked about Arimidex. I ended 5 yrs on arimidex in Nov 2010. Log in or register to post comments; cats_toy. Perhaps the data available are still not that mature to arrive at a conclusion. “The study showed that extended adjuvant therapy with an aromatase inhibitor results in a small but potentially important benefit,” said Terry Mamounas, M.D., M.P.H., medical director of the University of Florida Health Cancer Center and lead researcher of the study. Not sure if that helps any but the decision would be to each person and how they handle it. Posted 7 months ago ... Was put on Arimidex for 5 yrs. I could not tolerate Arimidex, because of the severe joint pain. After surgery, all women received tamoxifen for 2 years. that gives an idea of how your body might react to NOT having a drug in it that had a 5 yr build up in your system. I am in my late 50’s now. But meantime the partial mastectomy apparently did not heal properly & drains & is sometimes painful. Standard treatment for estrogen … You may discontinue taking Arimidex after 5 years. Read 0 Responses. Letrozole and anastrozole (Arimidex) are both aromatase inhibitors and are very similar to one another. No longer do they blindly follow the advice of doctors to take medication for the next five to 10 years that may or may not prevent the recurrence of breast cancer. I had a lump and lymph node ectomy (six nodes were removed) and the surgeon said he got all of it. To stay logged in, please refresh the page or, if you are working I also have fibromyalgia and chronic fatigue. i wasn’t sure what to expect. After surgery, the women were randomly assigned to one of four groups: 5 years of letrozole (letrozole monotherapy), 5 years of tamoxifen (tamoxifen monotherapy), or one of the two sequential treatment groups. I do realize they're very different drugs, but thought I would mention there's new research suggesting that women should consider staying on Tamoxifen for 10 years, instead of the 5 years that's been recommended for decades. The women in this study were followed for an additional 5 years after they stopped taking Arimidex. JavaScript is disabled in your web browser! Regards Okkie Vermeulen Answer Question. Follow - 2. Women are … He said that the studies shows that 2 years was better than 1, that 5 years was better than 2 but the 10 year study did not show any increase in protection over 5 years and that is why they say 5. And after 3 years, as good results from the new aromatase inhitors continued to accumulate, I switched to Arimidex, which I took for 5 more years. I am asking for input on this decision. After surgery, all women received tamoxifen for 2 years. I will be having my last treatment of 10 tomorrow. This site does not provide medical advice, diagnosis, or treatment. She also said something else will come along in the 10 year period that may be better, quicker. Taking an AI, either alone or after tamoxifen, has been shown to work better than taking just tamoxifen for 5 years. I had stage 111b breast cancer 11 1/2 years ago. Stopping aromatase inhibitors early I stopped taking my Arimidex after three years because I was having endless muscle aches and too many urinary tract infections. No drastic changes occurred. The researchers collected data on cancer recurrences, new cancers, heart disease, and deaths from any cause through April 2010. I also took Arimidex,Aromasan, Femara. Has anyone stopped this drug and had any withdrawal symptoms? The phase IV clinical study is created by eHealthMe based on reports of 19,912 people who have side effects when taking Arimidex from the FDA, and is updated regularly. How much does Arimidex increase survival? Barbara, according to my radiologist when we talked about Arimidex. I assume you have discussed switching AIs with your oncologist? Or you might have one of these drugs for 2 years followed by tamoxifen for 3 years. And at the end of the 5 years you have osteoporosis. However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. In most cases, Arimidex is taken for five years, although some women may take it for a shorter period. He told me that if I do ok on med, then he may keep me on for 15 years. What a relief. You have to do what’s feels right for you. If you can tolerate it then maybe it would not hurt to continue. I had concerns about the hot flashes and joint pain and was told about an antidepressant that they prescribe to conteract but I don’t like antidepressant. The radiation is to the T9, and Right femur bone. Last month, ... Was put on Arimidex for 5 yrs. (800) 925-4456 | I will be off my 5 years of Arimidexin Dec 2011 and have the same question.I have read many posts where women have stated that losing weight is so very much easier once off of Arimidex or Aromasin. I know the studies of 10 vs 5 are not out yet but Tamoxifen studies came out with 10 as a better choice for hormone positive, large tumors. Privacy Policy | Or.., "No more! She will be stopping her five year course soon and we will appreciate advice on what to expect (positive and negative side effects) after stopping the Arimidex treatment. Surely there is info out there. My wife was on Arimidex for 5 years following a mastectomy, chemo and reconstruction. Answer Question. Revised May 2018. I had a lumpectomy, chemo and radiation and was estrogen receptor positive. Dear nannyct, The current data with "extended adjuvant therapy" (beyond the initial 5 years) is with letrozole (Femara) after 5 years of tamoxifen. The doctors don't seem to know what to expect after longterm Arimidex … I am one year down with 4 to go. Symptoms after quitting arimidex Posted by sandrajo @sandrajo , Apr 11, 2019 Stopped taking arimedex several months ago but some symptoms persist: Fatigue, hair … These results, taken together with results from previous trials of 5 years of tamoxifen treatment versus none, suggest that 10 years of tamoxifen treatment can approximately halve breast cancer … The BCI test provides: 1) a quantitative estimate of the risk for both late (post-5 years from diagnosis) distant recurrence and of the cumulative distant recurrence risk over 10 years (0-10y) in patients treated with adjuvant endocrine therapy (LN- patients) or adjuvant chemoendocrine therapy (LN+ patients), and 2) prediction of the likelihood of benefit from extended (>5 year) endocrine therapy. They may be able to offer ways of improving your symptoms. So many advances being made now. Taking an AI, either alone or after tamoxifen, has been shown to work better than taking just tamoxifen for 5 years. I don’t have to decide immediately since dr wants to wait til chemo is more out of my system. As a charter member of a breast cancer support group, you wont believe how many women I have spoken to who couldn’t tell me what kind of breast cancer they had or what stage they were! 56 years old & been on arimadex 15 months now. I like the points you make, Lynette. Please enable this It is lobular, estrogen positive, and very rare. One of his nurses had hit the 5 year mark and says she will continue. Generally I was ok taking it, I didn't really struggle with side effects. I feel so very fortunate to have great doctors. I think she is brilliant and I trust her completely. Oncologist insisted I "needed" the drug. Patient Engagement Portal v.6.0 | He said to stop it for 2 weeks, on day 8 I felt normal. Symptoms after quitting arimidex Posted by sandrajo @sandrajo , Apr 11, 2019 Stopped taking arimedex several months ago but some symptoms persist: Fatigue, hair thinning, profuse sweating. Hi, Roseann - I'm premenopausal, so am on Tamoxifen, not Arimidex. Your specialist may suggest changing to a different aromatase inhibitor such as letrozole or exemestane, or another hormone treatment, as some women get on better with a different drug. switched it to 5 years. Dr says it didn’t heal properly which left a fold & therefore will need more surgery to fix. I had lost my mom due to a sudden heart attack and she was only 54 yrs young, so that drug was no in the cards for me. I took Femara for 9 months before switching to Arimidex, I was off of Femara for two weeks before starting the Arimidex. © 2021 Navigating Care, Inc. The phase IV clinical study is created by eHealthMe based on reports of 19,912 people who have side effects when taking Arimidex from the FDA, and is updated regularly. Stopping Arimidex Okkie. It has been 5 years since I started the drug after breast cancer surgery and radiation. Lots of Hugs, Janelle. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. Try searching for what you seek or ask your own question. I won’t start until Sept when I am done w/ my Herceptin treatments. If your bones are already beginning to show signs of thinning or if you already have osteoporosis, you may be given another drug to increase bone density and strength. He said that the studies shows that 2 years was better than 1, that 5 years was better than 2 but the 10 year study did not show any increase in protection over 5 years and that is why they say 5. The radiologist also said that even taking the pill for a year was better than not at all. I am a 41 year old IIb breast cancer patient. I was recently diagnosed with breast cancer mestases to the bones. It is just trial & error, and you have to consider you “quality of life” And whatever you choose is YOUR decision to make, not the Dr, or anyone else. 1,918 postmenopausal women were enrolled in the trial and half of them were assigned to either take letrozole for five additional years (after already taking it for five years), the other half were given a placebo. Will never take it again.I don't care if my recurrence rate is the 5% or half of that, meaningless. Your user session will expire in 2 minutes. HIGHLIGHTS OF PRESCRIBING INFORMATION. My wife is due to stop Arimidex after 5 years. Has anyone out there also stopped Arimidex after many years? Stopping Arimidex After 3 Years However, your hair should return to the way it was before treatment when you stop taking anastrozole. Treatment adherence was similar among both groups, with 74.6% of patients on Arimidex following the treatment regimen for the full five years and 77% following through in the placebo group. Now? Available for Android and iOS devices. Arimidex followed the original 5 year study on Tamoxifen and wondering if anyone has gone off Arimidex after 5 years … Aromatase inhibitors include: anastrozole (Arimidex) letrozole (Femara) exemestane (Aromasin) You are most likely to have anastrozole or letrozole for 5 years. i wasn’t sure what to expect. There was recently a new study published that says 10 years is better than 5 and the new standard. Report . Many women worry that stopping Arimidex after five years will cause their cancer to come back; however, the International Breast Cancer Intervention Study II …

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